Is the String Db String MCP server down?

mcp-registry/org.string-db/string-mcp · v2.14.7

Also listed as glama/meringlab/string-mcp

healthy
Last checked 2026-10-17 07:26 UTC · handshake 1.8s

As of 2026-10-17 07:26 UTC, the String Db String MCP server is up with a Glimind reliability score of 96/100 (grade A). Over the last 30 days it answered 100% of Glimind's liveness checks.

uptime (30d checks)
100%
checks observed
3,643
outages (90d)
0
tools
25

Query STRING interactions, enrichment, annotations, homology, and PPI networks.

Install String Db String MCP server

Add to Cursor Add to VS Code

Claude Code

claude mcp add --transport http string-db-string-mcp-server https://mcp.string-db.org/

Claude Desktop · Windsurf · Cline (mcpServers JSON)

{
  "mcpServers": {
    "string-db-string-mcp-server": {
      "type": "http",
      "url": "https://mcp.string-db.org/"
    }
  }
}

Third-party server, listed as discovered. Review its source before installing.

Agent-readiness: B (82/100)

B (82/100): 0 error(s), 3 warning(s) across 17 tool(s); ~8,181 tokens of tool definitions.
Scores higher than 40% of 15,259 MCP servers Glimind has audited.
Its tool list costs an agent ~8,181 tokens per session — more than 65% of servers.
no tool-poisoning patterns
Schemas100
Descriptions100
Safety hints15
Token cost100
Client compatibility100
Protocol100
Reliability85
Stability20

What to fix (4)

17 of 17 tool(s) carry no readOnlyHint/destructiveHint annotations.

Annotate read-only tools with {"readOnlyHint": true}. Agents and gateways can then run them without a confirmation prompt, and route around destructive ones.

Tools: string_all_interaction_partners, string_create_file, string_enrichment, string_enrichment_image_url, string_functional_annotation and 12 more

1 tool(s) look like they change state (create/send/delete/pay…) but declare no destructiveHint.

Set annotations {"readOnlyHint": false, "destructiveHint": true|false, "idempotentHint": …}. Clients use these to ask the user before a side effect and to auto-approve safe reads.

Tools: string_create_file

Handshake + tools/list takes ~2,239 ms.

Serve tools/list from memory, keep the process warm, and host close to your users. Every new agent session pays this before its first call.

In the last 30 days: 0 tool(s) removed and 33 schema change(s).

Add new tools or optional parameters instead of renaming or removing; deprecate first (say so in the description) and remove later. Agents cache tool contracts.

Auto-fix: 13 corrected tool definitions

Paste-ready definitions with the problems above fixed. Changes marked verify need a human look. All of them as JSON: /v1/readiness/mcp-registry%2Forg.string-db%2Fstring-mcp/fixes

string_all_interaction_partners 1 change
{
  "name": "string_all_interaction_partners",
  "description": "Retrieves all interaction partners for one or more proteins from STRING.\n\nThis tool returns all known interactions between your query protein(s) and **any other proteins in the STRING database**.\n\n- Use this when asking **“What does TP53 interact with?”**\n- It differs from `string_interactions_query_set`, which only shows interactions **within the input set** or a limited extension of it.\n\nYou can filter for strong interactions using `required_score`.\n\n- Evidence scores:  \n    `nscore` (neighbor",
  "inputSchema": {
    "type": "object",
    "required": [
      "identifiers"
    ],
    "properties": {
      "species": {
        "type": "string",
        "default": null,
        "description": "NCBI taxonomy ID (e.g. 9606 for human) or STRING genome ID (e.g. STRG0AXXXXX for uploaded genomes). Only set when required."
      },
      "identifiers": {
        "type": "string",
        "examples": [
          "TP53%0dSMO"
        ],
        "description": "One or more protein identifiers, separated by carriage return (%0d)."
      },
      "network_type": {
        "anyOf": [
          {
            "enum": [
              "functional",
              "physical",
              "regulatory"
            ],
            "type": "string"
          },
          {
            "type": "null"
          }
        ],
        "default": null,
        "description": "Omit for the default functional network. Its typed view can include physical and directed regulatory attributes when STRING returns them; inspect `physical` and `regulatory.directions` before claiming those edge types. Set physical for binding, complex, or co-complex questions. Set regulatory for directed regulatory relationships between proteins."
      },
      "network_flavor": {
        "anyOf": [
          {
            "enum": [
              "evidence",
              "confidence",
              "typed"
            ],
            "type": "string"
          },
          {
            "type": "null"
          }
        ],
        "default": null,
        "description": "Defaults are typed for functional networks, evidence for physical networks, and confidence for regulatory networks. Typed returns functional pairs with any physical and directed regulatory attributes that STRING reports; it does not make every pair physical or regulatory. Typed is available only for functional networks. Set evidence or confidence only when the user requests that edge display style."
      },
      "required_score": {
        "anyOf": [
          {
            "type": "integer",
            "maximum": 1000,
            "minimum": 0
          },
          {
            "type": "null"
          }
        ],
        "default": null,
        "description": "Minimum interaction score to include. Omit unless a confidence threshold is requested or a broader/narrower threshold is needed."
      }
    }
  },
  "annotations": {
    "readOnlyHint": true
  },
  "title": "STRING: Get all interaction partners for proteins"
}
string_create_file 1 change
{
  "name": "string_create_file",
  "description": "Creates a downloadable file for STRING-derived results.\n\nUse this tool when the user explicitly asks to download, save, export,\nor receive a file containing STRING data, tables, protein lists,\nenrichment results, networks, etc.\n\nWhen a response would otherwise include a publication-style or supplementary\nresult table, or another table clearly intended for reuse outside chat,\nmention that a downloadable TSV/CSV file can be generated on request. Ask\nwhether they want the file, unless they already ",
  "inputSchema": {
    "type": "object",
    "required": [
      "filename",
      "content"
    ],
    "properties": {
      "content": {
        "type": "string",
        "description": "STRING-derived file content. For .tsv/.csv: one rectangular table, one header row, matching delimiter, no Markdown/prose/repeated headers/multiple tables. Use one row per entity, edge, cluster member, annotation, or enrichment term. Use bare numeric scores/FDR/p-values; put interpretation and caveats in chat or .md/.txt."
      },
      "filename": {
        "type": "string",
        "examples": [
          "string-enrichment.tsv"
        ],
        "description": "Suggested output filename with a safe extension such as .tsv, .csv, .json, .md, or .txt. Match content to the extension; prefer .tsv for reusable tabular STRING data. Use a concise name that reflects the STRING analysis result."
      }
    }
  },
  "annotations": {
    "readOnlyHint": false,
    "destructiveHint": false,
    "idempotentHint": false
  },
  "title": "STRING: Create a downloadable STRING result file"
}
string_enrichment_image_url 1 change
{
  "name": "string_enrichment_image_url",
  "description": "Retrieves a STRING enrichment figure (image URL) for a set of proteins. For the enriched terms and FDR values, use `string_enrichment`.\n\n- Each figure shows a single enrichment category; call again with another `category` to show a different one.\n- Use the same proteins and species as the network and enrichment results already shown to the user, so the figure matches them.",
  "inputSchema": {
    "type": "object",
    "required": [
      "identifiers"
    ],
    "properties": {
      "x_axis": {
        "anyOf": [
          {
            "enum": [
              "signal",
              "strength",
              "FDR",
              "gene_count"
            ],
            "type": "string"
          },
          {
            "type": "null"
          }
        ],
        "default": null,
        "description": "Value shown on the X-axis; also selects and orders the terms. If omitted, STRING uses signal."
      },
      "species": {
        "type": "string",
        "default": null,
        "description": "NCBI/STRING taxon (e.g. 9606 for human, or STRG0AXXXXX)."
      },
      "category": {
        "anyOf": [
          {
            "enum": [
              "Process",
              "Function",
              "Component",
              "Keyword",
              "KEGG",
              "RCTM",
              "HPO",
              "MPO",
              "DPO",
              "WPO",
              "ZPO",
              "FYPO",
              "GWAS",
              "Hallmark",
              "Pfam",
              "SMART",
              "InterPro",
              "PMID",
              "NetworkNeighborAL",
              "COMPARTMENTS",
              "TISSUES",
              "DISEASES",
              "WikiPathways"
            ],
            "type": "string"
          },
          {
            "type": "null"
          }
        ],
        "default": null,
        "description": "Term category for enrichment. If omitted, STRING uses Process. Use Process/Function/Component for GO, KEGG for KEGG pathways, RCTM for Reactome, and PMID for publications."
      },
      "graph_type": {
        "anyOf": [
          {
            "enum": [
              "dotplot",
              "barplot"
            ],
            "type": "string"
          },
          {
            "type": "null"
          }
        ],
        "default": null,
        "description": "Plot type: dotplot or barplot (horizontal bar chart). If omitted, STRING uses dotplot."
      },
      "identifiers": {
        "type": "string",
        "examples": [
          "SMO%0dTP53"
        ],
        "description": "Protein identifiers, separated by %0d."
      },
      "color_palette": {
        "anyOf": [
          {
            "enum": [
              "mint_blue",
              "red_blue",
              "lime_emerald",
              "green_blue",
              "peach_purple",
              "straw_navy",
              "yellow_pink"
            ],
            "type": "string"
          },
          {
            "type": "null"
          }
        ],
        "default": null,
        "description": "Color palette for FDR. If omitted, STRING uses mint_blue."
      },
      "group_by_similarity": {
        "anyOf": [
          {
            "type": "number",
            "maximum": 1,
            "minimum": 0.1
          },
          {
            "type": "null"
          }
        ],
        "default": null,
        "description": "Visually groups terms based on term similarity. Default: 0.8. Details: string_help topic 'enrichment_grouping'."
      },
      "number_of_terms_shown": {
        "anyOf": [
          {
            "type": "integer",
            "minimum": 1
          },
          {
            "type": "null"
          }
        ],
        "default": null,
        "description": "Max number of terms shown on plot. Default: 10."
      }
    }
  },
  "annotations": {
    "readOnlyHint": true
  },
  "title": "STRING: Get enrichment result figure (image URL)"
}

Get alerted

Get an email or webhook when this server's readiness drops by 10+ points, tool-poisoning text appears, or a tool breaks:

curl -X POST https://glimind.com/v1/subscriptions -H 'content-type: application/json' -d '{"tools":["mcp-registry/org.string-db/string-mcp"],"email":"[email protected]"}'

Agents: watch_tool({"toolId": "mcp-registry/org.string-db/string-mcp"}) over MCP.

Passed

Largest tool definitions

Static checks of the advertised tools/list (schema, descriptions, annotations, tool-poisoning patterns, names, size) plus observed protocol, uptime, latency and contract changes. Read-only: no tool is ever called. Weights: schema 15, docs 20, safety 15, efficiency 15, compatibility 15, protocol 5, reliability 10, stability 5. Token counts are estimates (~3.6 characters per token).

Operator? Fix these, then re-check live. Embed the readiness badge:

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Tool-definition log

Glimind records every version of this server's tool definitions in a signed, append-only transparency log. Current manifest sha256:846ecdc0d95ad5a5…, first seen 2026-10-17, included at leaf 14012 of 17,120. Version history · verify what your client received.

Tools (25)

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Add to Cursor Add to VS Code

Claude Code

claude mcp add --transport http glimind https://glimind.com/mcp

Claude Desktop · Windsurf · Cline (mcpServers JSON)

{
  "mcpServers": {
    "glimind": {
      "type": "http",
      "url": "https://glimind.com/mcp"
    }
  }
}

FAQ

Is the String Db String MCP server down right now?

As of 2026-10-17 07:26 UTC, the String Db String MCP server is up with a Glimind reliability score of 96/100 (grade A). Over the last 30 days it answered 100% of Glimind's liveness checks.

How many tools does String Db String MCP server provide?

String Db String MCP server advertises 25 tools, including access_evidence_links, cluster_and_visualize_network, functional_enrichment_analysis, get_functional_annotations, homology_lookup.

How do I install String Db String MCP server?

Point your MCP client at this streamable-http endpoint: https://mcp.string-db.org/

Is the String Db String MCP server safe to connect to an AI agent?

Glimind scanned all 17 tool definitions for tool-poisoning patterns — hidden or invisible characters, instructions that override the model, concealment from the user, requests to read credential or MCP config files, conversation exfiltration and cross-tool shadowing — and found none. This checks what the server tells the model, not what its code does; review the source before granting access to sensitive data.

Operator of String Db String MCP server?

Status page: 90-day uptime, every outage and how long it lasted.

Claim this listing to get the Verified operator marker, a remediation checklist and owner analytics, or embed the live badge from any of the tool pages above. Maintainers: alerts, deploy attestation and monthly reports.

Status is an automated estimate from Glimind's liveness checks (handshake and tool listing only; no tool is ever called) and may lag or differ from your network. Glimind is not affiliated with this server or its operator. Operator? Request a correction or opt out at https://glimind.com/opt-out.